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Article

Comprehensive assessment of Indian variations in the druggable kinome landscape highlights distinct insights at the sequence, structure and pharmacogenomic stratum

2021-05-26

Abstract excerpt

India confines more than 17% of the world’s population and has a diverse genetic makeup with several clinically relevant rare mutations belonging to many sub-group which are undervalued in global sequencing datasets like the 1000 Genome data (1KG) containing limited samples for Indian ethnicity. Such databases are critical for the pharmaceutical and drug development industry where the diversity plays a crucial rol...

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Literature Corpus work
c43b8168-ab6c-5292-95fc-414b051ed581
DOI
10.1101/2021.05.23.445314
Open publication

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Comprehensive assessment of Indian variations in the druggable kinome landscape highlights distinct insights at the sequence, structure and pharmacogenomic stratumDOI 10.1101/2021.05.23.445314
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