Article

Interpretation of biological experiments changes with evolution of Gene Ontology and its annotations

2017-12-03

Abstract excerpt

<h4>ABSTRACT</h4> Gene Ontology (GO) enrichment analysis is ubiquitously used for interpreting high throughput molecular data and generating hypotheses about underlying biological phenomena of experiments. However, the two building blocks of this analysis — the ontology and the annotations — evolve rapidly. We used gene signatures derived from 104 disease analyses to systematically evaluate how enrichment analysi...

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Literature Corpus work: c3f1ca77-f9b5-5022-8d70-9de3018a582c
DOI: 10.1101/228080

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