Article
<i>Staphylococcus pasteuri</i> isolates ( <i>Spvs</i> ) from human atherosclerotic plaques mediate virulence, intracellular resistance and transendothelial invasion of macrophages: A mechanistic paradigm for microbial pathogenicity in atherosclerosis
2019-08-01
Abstract excerpt
Atherosclerotic cardiovascular disease, a chronic inflammatory condition of multifactorial etiology, is the leading cause of death worldwide. The concept of ‘bacterial persistence’ has been proposed as one of several contributing factors to this disease. We hypothesized that the infectious agent(s) found at the site of the atheroma may be dormant but perpetuate virulence in response to host defense and other physi...
Topics
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- Antimicrobial Resistance in Staphylococcus
- Bacterial Infections and Vaccines
- Bartonella species infections research
- Fungal Infections and Studies
- Infective Endocarditis Diagnosis and Management
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Parasitic Infections and Diagnostics
- Vector-borne infectious diseases
Identifiers and source
- Literature Corpus work
- c3f1075d-45f9-5fee-b11c-8745cc3aa9f5
- DOI
- 10.1101/721571
