Article

A functional artificial neural network for noninvasive presurgical evaluation of glioblastoma multiforme prognosis and radiosensitivity profiling

2020-12-16

Abstract excerpt

<h4>Background and Purpose</h4> Genetic profiling for glioblastoma multiforme (GBM) patients with intracranial biopsy carries a significant risk of permanent morbidity. We previously demonstrated that the CUL2 gene, encoding the scaffold cullin2 protein in the cullin2-RING E3 ligase (CRL2), can predict GBM radiosensitivity and prognosis mainly due to the functional involvement of CRL2 in mediating hypoxia-induci...

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Literature Corpus work: c3853466-ce05-5aaa-b7d2-3f16ccbfb108
DOI: 10.1101/2020.12.15.422749

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