Article

Characterising tandem repeat complexities across long-read sequencing platforms with TREAT and otter

2024-03-17

Abstract excerpt

Tandem repeats (TR) play important roles in genomic variation and disease risk in humans. Long-read sequencing allows for the accurate characterisation of TRs, however, the underlying bioinformatics perspectives remain challenging. We present otter and TREAT: otter is a fast targeted local assembler, cross-compatible across different sequencing platforms. It is integrated in TREAT, an end-to-end workflow for TR ch...

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Literature Corpus work: c2db45b3-9365-5ee0-9ba6-451ea676377d
DOI: 10.1101/2024.03.15.585288

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