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Expression of PGC-1α, PPAR-α and UCP1 genes, metabolic and anthropometric factors in response to sodium butyrate supplementation in patients with obesity: A triple-blind, randomized placebo-controlled clinical trial

2024-03-25

Abstract excerpt

<title>Abstract</title> <p><bold>Objective </bold>There is increasing evidence that gut metabolites have a role in the etiology of obesity. This study aimed to investigate the effects of sodium butyrate (NaB) supplementation on the expression of peroxisome proliferator activated-receptor (PPAR) gamma coactivator -1α (PGC- 1α), PPAR-α, and uncoupling protein 1 (UCP1) genes, as well as on metabolic parameters and a...

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Literature Corpus work
c2b43724-e239-5518-aa71-10388a814393
DOI
10.21203/rs.3.rs-4133322/v1
Open publication

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