Article

Hub Genes and Key Pathway Identification in Wilms Tumor Based on Bioinformatics Analysis

2020-12-22

Abstract excerpt

<title>Abstract</title> <p>Wilms tumor (WT) is a childhood kidney cancer with unknown etiology. Gene expression analysis has become very essential in WT. Thus, we performed an integrated analysis of gene expression data to identify new molecular mechanisms and key functional genes in WT. Gene expression (GSE60850) dataset was downloaded from Gene Expression Omnibus. Differentially expressed genes (DEGs) were iden...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: c2773f0c-8f6a-54c4-ba94-a185797610b2
DOI: 10.21203/rs.3.rs-133323/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Hub Genes and Key Pathway Identification in Wilms Tumor Based on Bioinformatics AnalysisDOI 10.21203/rs.3.rs-133323/v1Read

Screening of potential hub genes involved in Kidney Wilms tumor via bioinformatics analysis and experimental validationSemantic proximity Read

Bioinformatical analysis of the key differentially expressed genes for screening potential biomarkers in Wilms tumorSemantic proximity Read

Bioinformatics analysis and identification of genes and pathways involved in patients with Wilms tumorSemantic proximity Read

Weighted gene co‑expression network analysis for identifying hub genes in association with prognosis in Wilms tumorSemantic proximity Read

Exploration of biological significance of m6A-related genes in Wilms tumorSemantic proximity Read

Identification of the potential novel biomarkers as susceptibility gene for Wilms tumor.Semantic proximity Read

Application of Bioinformatics Analysis to Identify Important Pathways and Hub Genes in Ovarian Cancer Affected by WT1Semantic proximity Read

Cyclin B1 is a novel prognostic biomarker and promotes proliferation, migration and invasion in Wilms TumourSemantic proximity Read

Investigating the dysfunctional pathogenesis of Wilms’ tumor through a multidimensional integration strategySemantic proximity Read

Multi-Omics and Machine Learning Integration of Diverse Cell Death Pathways Optimize Risk Stratification and Inform Drug Therapy in Wilms TumorSemantic proximity Read

Identification of Prognosis-Related RBPs to Reveal The Role of RNA Binding Proteins in the Progression and Prognosis of Wilms’ TumorSemantic proximity Read

Identification and Validation of Cuproptosis-Related LncRNA Signatures as a Novel Prognostic Model for Wilms TumorSemantic proximity Read