Article

Correlating High-dimensional longitudinal microbial features with time-varying outcomes with FLORAL

2025-02-19

Abstract excerpt

Correlating time-dependent patient characteristics and matched microbiome samples can identify biomarkers in longitudinal microbiome studies. Existing approaches typically repeat a pre-specified modeling approach for all taxonomic features, followed by a multiple testing adjustment step for false discovery rate (FDR) control. In this work, we develop an alternative strategy of using log-ratio penalized generalized...

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Literature Corpus work: c1afd943-3373-5226-9c1e-3ec2acc51d43
DOI: 10.1101/2025.02.17.638558

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