Article

NOTCH2NLC GCC repeats are not expanded in Italian Amyotrophic Lateral Sclerosis patients

2022-03-21

Abstract excerpt

<h4>Introduction: </h4> Repeat expansions in genes other than C9orf72 and ATXN2 have been recently associated with Amyotrophic Lateral Sclerosis (ALS). Indeed, an abnormal number of GGC repeats in NOTCH2NLC has been recently reported in 0.7% of sporadic ALS patients from mainland China. This finding was not confirmed in an ALS cohort of subjects from Taiwan. As the involvement of expanded NOTCH2NLC alleles in ALS...

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Literature Corpus work: bef2089d-f66e-5021-8a98-a099f38d1947
DOI: 10.21203/rs.3.rs-1459096/v1

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