Article
Transcriptomic Profiling of Primary Human Dermal Fibroblasts Response to Perlatolic Acid and Bromoatranorin
2026-07-23
Abstract excerpt
<h4>Background: </h4> Secondary metabolites of lichens have a wide range of biological activity, including geroprotective activity, but their complex effect on the human transcriptome remains poorly understood. The aim of the study was to evaluate the effects of perlatolic acid (PA) and bromoatranorine (Br) on the transcriptomic profile of primary human dermal fibroblasts (HDFs) to identify key target genes and si...
Topics
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- Autoimmune Bullous Skin Diseases
- Cell Adhesion Molecules Research
- Dermatology and Skin Diseases
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Medical Imaging and Pathology Studies
- Occupational and environmental lung diseases
- Skin and Cellular Biology Research
- Systemic Sclerosis and Related Diseases
Identifiers and source
- Literature Corpus work
- be9cacca-3cdb-5430-81a5-404d534e81f1
- DOI
- 10.20944/preprints202607.1735.v1
