Article

Developmental origins of disease : intra-uterine programming of offspring metabolic function and long-term markers of health

2021-01-01

Abstract excerpt

It is widely acknowledged that maternal obesity and metabolic disorder during pregnancy may trigger long-lasting cardiovascular dysfunction in the mother. In obese pregnancy, there is progressive insulin resistance and a systemic inflammatory end-organ structure and function. Emerging evidence suggests that the offspring may also be subject to these metabolic changes and endure these long-lasting effects. The 'Dev...

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Literature Corpus work: be6ca461-47af-5efa-ab53-d913e442a4c8
DOI: 10.5525/gla.thesis.82085

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