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Berberine, the major bioactive compound from <i>Berberis aristata,</i> attenuates virulence of multidrug resistant <i>Chromobacterium violaceum</i> at non-lethal concentrations by targeting bacterial efflux and denitrification machinery

2025-10-18

Abstract excerpt

Berberis aristata root extract, and berberine were assessed for their anti-pathogenic activity against multidrug resistant Chromobacterium violaceum . Berberine was found to be more potent than the parent extract with respect to attenuation of the pathogen’s virulence against the model host Caenorhabditis elegans. It also performed better than six different antibiotics, when compared at same concentration. Berbe...

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Literature Corpus work
bd53dd6f-4877-560f-9f7e-2d15a3a55399
DOI
10.1101/2025.10.17.683191
Open publication

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Berberine, the major bioactive compound from <i>Berberis aristata,</i> attenuates virulence of multidrug resistant <i>Chromobacterium violaceum</i> at non-lethal concentrations by targeting bacterial efflux and denitrification machineryDOI 10.1101/2025.10.17.683191
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