Article

Design, Synthesis, and Biological Evaluation of Light-Activated Antibiotics

2021-01-12

Abstract excerpt

The spatial and temporal control of bioactivity of small molecules by light (photopharmacology) constitutes a promising approach for study of biological processes and ultimately for the treatment of diseases. In this study, we investigated two different ‘caged’ antibiotic classes that can undergo remote activation with UV-light at λ=365 nm, via the conjugation of deactivating and photocleavable units through a sho...

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Literature Corpus work: bd2bcccd-da19-57aa-a117-2c1e7106c373
DOI: 10.26434/chemrxiv.13553885.v1

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