Back to search

Article

Unveiling the Role of Melatonin in Coronary Heart Disease: Identification and Experimental Validation of Novel Biomarkers

2026-04-21

Abstract excerpt

<title>Abstract</title> <p>Melatonin (ME) affects multiple systems in coronary heart disease (CHD), including lipid/glucose metabolism, blood pressure, and sleep-wake regulation, while also promoting coronary thrombosis through unknown mechanisms. This study uses bioinformatics to identify ME-related biomarkers for CHD diagnosis and treatment. The GSE179789 and GSE113079 datasets were obtained from a public datab...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
bcf27c60-2f55-51ff-877b-d559cdb74c6a
DOI
10.21203/rs.3.rs-8816168/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Unveiling the Role of Melatonin in Coronary Heart Disease: Identification and Experimental Validation of Novel BiomarkersDOI 10.21203/rs.3.rs-8816168/v1
Unveiling miRNA Biomarkers for Hypertrophic Cardiomyopathy through Integrated Bioinformatics and Machine Learning AnalysisSemantic proximity
Exploration of potential miRNA biomarkers in coronary heart disease and their correlation with clinical symptoms: cross-sectional studySemantic proximity
Melatonin and Regulation of miRNAs: Novel Targeted Therapy for Cancerous and Noncancerous DiseaseSemantic proximity
Integrative Genomic and Computational Drug Discovery Approach to Unveil Key Pathways and Therapeutic Targets in Coronary Artery DiseaseSemantic proximity
The role of melatonin in epigenetic regulation of various diseases.Semantic proximity
Insomnia score: predictive ability of insomnia, high-diagnostic and prognostic value for cancerSemantic proximity
Exploring the Therapeutic Potential of Danshen (Salvia Miltiorrhiza) and Ginkgo Biloba in Coronary Heart Diseases: A Network Pharmacology InvestigationSemantic proximity
Identification of novel loci regulating circulating melatonin and its causal relationship with hypertension.Semantic proximity
Melatonin-Related Genes as Key Players in Alzheimer's Disease: Discovery of Promising Biomarkers for Treatment Targets for Alzheimer's DiseaseSemantic proximity
A bibliometric analysis of research hotspots and cutting-edge trends in cardiovascular disease biomarkersSemantic proximity
Bioinformatics Analysis of Gene Network of Thyroid Disorders and Coronary Artery DiseasesSemantic proximity
Mediation analysis of metabolic and inflammatory factors on the association between sleep apnoea and coronary heart disease in the large population–based cohortSemantic proximity
Select a neighboring publication to make it the new centre.