Article

Mathematical modelling of the effects of health interventions on the evolution of life history in disease-causing organisms

2013-01-01

Abstract excerpt

We use mathematical models to explore the evolutionary implications of health interventions affecting age-dependent mortality schedules in two contexts, antihelminthics targeting parasitic nematodes, and programs directed against malaria vectors. We show that interventions targeting parasitic nematodes can exert selection pressure to either shorten or extend the time to maturity, depending on the details of worm m...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: bcedad50-cfeb-5598-a701-4696facc2bc0
DOI: 10.21954/ou.ro.0000f0e1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Mathematical modelling of the effects of health interventions on the evolution of life history in disease-causing organismsDOI 10.21954/ou.ro.0000f0e1Read

Multiple blood feeding in mosquitoes shortens the <i>Plasmodium falciparum</i> incubation period and increases malaria transmission potentialSemantic proximity Read

Eco-evolutionary dynamics of anthelmintic resistance in soil-transmitted helminthsSemantic proximity Read

Multiple blood feeding in mosquitoes shortens the Plasmodium falciparum incubation period and increases malaria transmission potentialSemantic proximity Read

<i>Plasmodium</i> infection decreases fecundity and increases survival of mosquitoesSemantic proximity Read

Mosquito ageing modulates the development, virulence and transmission potential of pathogensSemantic proximity Read

Infection Age as a Predictor of Epidemiological Metrics for MalariaSemantic proximity Read

No evidence for a classic transmission-duration tradeoff in human malaria infectionsSemantic proximity Read

Agroclimatic Impact on Gastrointestinal Infection: A Mathematical ModelSemantic proximity Read

Larval diet and temperature alter mosquito immunity and development: using body size and developmental traits to track carry-over effects on longevitySemantic proximity Read

Population biology of malaria within the mosquito: density-dependent processes and potential implications for transmission-blocking interventionsSemantic proximity Read

Quantification of anti-parasite and anti-disease immunity to malaria as a function of age and exposure.Semantic proximity Read

Dynamic Patterns of Parasitism and Immunity across Host Development Influence Optimal Strategies of Resource Allocation.Semantic proximity Read