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Phenotype-guided post-triage of combined screening–positive pregnancies using an interpretable decision-tree model

2026-01-23

Abstract excerpt

<title>Abstract</title> <p>The first-trimester combined screening test (CST) increases aneuploidy risk but results in a substantial false-positive burden, with most CST-positive pregnancies ultimately being euploid. Optimizing decision-making within this already risk-enriched population remains a major clinical challenge. This retrospective observational study evaluated a phenotype-guided post-triage (PGT) model...

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Literature Corpus work
bcbbe057-bb1c-5136-a289-68073f3186eb
DOI
10.21203/rs.3.rs-8415161/v1
Open publication

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Phenotype-guided post-triage of combined screening–positive pregnancies using an interpretable decision-tree modelDOI 10.21203/rs.3.rs-8415161/v1
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