Synergy between Enterobacteriaceae and dietary components shapes the competition between the dominant anaerobes of the human gut

Abstract excerpt

The human gut microbiota is frequently dominated by the Bacteroidota phylum, with Bacteroidaceae and Prevotellaceae families prevailing in modern and traditional lifestyles, respectively. While these distinct profiles have been well-documented across cohorts, the underlying mechanisms remain poorly understood. Here, we combine defined gut community models and genetic tools to experimentally dissect the ecological...

Topics

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• Clostridium difficile and Clostridium perfringens research
• Diet and metabolism studies
• Diet, Metabolism, and Disease
• Gastrointestinal motility and disorders
• Gut microbiota and health
• Metabolomics and Mass Spectrometry Studies
• Microbial Metabolites in Food Biotechnology
• Probiotics and Fermented Foods

Identifiers and source

Literature Corpus work

bc960222-8325-5df8-b322-823f4fac02fb

DOI

10.1101/2025.09.03.673633