Article

Replication stress in activated human NK cells induces sensitivity to apoptosis

2023-09-07

Abstract excerpt

Natural killer cells are innate immune effectors that kill virally infected or malignant cells. Natural killer cell deficiency (NKD) occurs when NK cell development or function are impaired, and individuals with NKD are susceptible to severe and recurrent viral infections. Several gene deficiencies result in NKD, including variants in MCM4, GINS1, MCM10 and GINS4, which are components of the CDC45-MCM-GINS (CMG) h...

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Literature Corpus work: bc5d9434-4806-5a71-b92c-c52d1a320750
DOI: 10.1101/2023.09.07.556586

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