Vaginal microbial dynamics and pathogen colonization in a humanized microbiota mouse model

Abstract excerpt

<h4>ABSTRACT</h4> Vaginal microbiota composition is associated with differential risk of urogenital infection. Although vaginal Lactobacillus spp. are thought to confer protection through acidification, bacteriocin production, and immunomodulation, lack of an in vivo model system that closely resembles the human vaginal microbiota remains a prominent barrier to mechanistic discovery. We performed 16S rRNA ampli...

Topics

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• Clostridium difficile and Clostridium perfringens research
• Gut microbiota and health
• Neonatal and Maternal Infections
• Pelvic floor disorders treatments
• Probiotics and Fermented Foods
• Reproductive System and Pregnancy
• Reproductive tract infections research
• Urinary Tract Infections Management

Identifiers and source

Literature Corpus work

bbe6de44-97f7-5a97-a371-ed3749d6b905

DOI

10.1101/2023.02.09.527909