Article

<strong>Attenuation and Degeneration of SARS-CoV-2 Despite of Adaptive Evolution</strong>

2022-11-23

Abstract excerpt

Evolution of SARS-CoV-2 has followed similar trends as other RNA viruses, e.g., HIV-1 and influenza A. Rapid initial diversification was followed by strong competition and rapid succession of dominant variants. Host-initiated RNA editing has been the primary mechanism for introducing mutations. A significant number of mutations were detrimental and were quickly purged. Fixed mutations are mostly diversifying mutat...

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Literature Corpus work: bb901c46-90a2-5d05-84e3-78d960840e3b
DOI: 10.20944/preprints202211.0430.v1

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