Article

LAP Drives Monocyte-Mediated and Extracellular Translocation of <i>Listeria monocytogenes</i> Across the Placental Barrier

2025-12-23

Abstract excerpt

<h4>ABSTRACT</h4> Listeria monocytogenes ( Lm ) is a major cause of fetal infection, yet the mechanisms by which it traverses the placental barrier remain incompletely defined. We established and validated a physiologically relevant in vitro human placental co-culture barrier model using BeWo trophoblasts and primary human placental vascular endothelial cells (HPVECs), which exhibited robust barrier integrity an...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: bb5f92f1-c739-530f-a74d-c93acaea4ad3
DOI: 10.64898/2025.12.22.696054

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

LAP Drives Monocyte-Mediated and Extracellular Translocation of <i>Listeria monocytogenes</i> Across the Placental BarrierDOI 10.64898/2025.12.22.696054Read

Vertical Transmission of Listeria monocytogenes: Probing the Balance between Protection from Pathogens and Fetal ToleranceSemantic proximity Read

Acute response to pathogens in the early human placenta at single-cell resolutionSemantic proximity Read

Invasive Extravillous Trophoblasts Restrict Intracellular Growth and Spread of Listeria monocytogenesSemantic proximity Read

<i>Listeria</i> adhesion protein orchestrates caveolae-mediated apical junctional remodeling of epithelial barrier for <i>L. monocytogenes</i> translocationSemantic proximity Read

<i>Listeria monocytogenes</i> InlP interacts with afadin and facilitates basement membrane crossingSemantic proximity Read

Recent advances in understanding Listeria monocytogenes infection: the importance of subcellular and physiological contextSemantic proximity Read

Listeria adhesion protein orchestrates caveolae-mediated apical junctional remodeling of epithelial barrier for Listeria monocytogenes translocationSemantic proximity Read

Infection with <i>Listeria monocytogenes</i> alters the placental transcriptome and eicosanomeSemantic proximity Read

Listeriosis in the Pregnant Guinea Pig: a Model of Vertical TransmissionSemantic proximity Read

Internalin B is essential for adhesion and mediates the invasion of Listeria monocytogenes into human endothelial cells.Semantic proximity Read

InlP, a New Virulence Factor with Strong Placental TropismSemantic proximity Read

RNAi screen reveals a role for PACSIN2 and caveolins during bacterial cell-to-cell spreadSemantic proximity Read