Back to search

Article

Metformin on Time to Sustained Recovery in Adults with COVID-19: The ACTIV-6 Randomized Clinical Trial

2025-01-14

Abstract excerpt

<h4>Importance</h4> The effect of metformin on reducing symptom duration among outpatient adults with coronavirus disease 2019 (COVID-19) has not been studied. <h4>Objective</h4> Assess metformin compared with placebo for symptom resolution during acute infection with SARS-CoV-2. <h4>Design, Setting, and Participants</h4> The ACTIV-6 platform evaluated repurposed medications for mild to moderate COVID-19. Between...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
ba43df22-a44b-5132-98cb-4198ab5925b4
DOI
10.1101/2025.01.13.25320485
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Metformin on Time to Sustained Recovery in Adults with COVID-19: The ACTIV-6 Randomized Clinical TrialDOI 10.1101/2025.01.13.25320485
Outpatient Treatment of COVID-19 and the Development of Long COVID Over 10 Months: A Multi-Center, Quadruple-Blind, Parallel Group Randomized Phase 3 TrialSemantic proximity
Effectiveness of Molnupiravir for the Treatment of COVID-19: A Systematic Literature Review of Real-World Observational StudiesSemantic proximity
Effectiveness of Molnupiravir for the Treatment of COVID-19: A Systematic Literature Review of Real-World Observational StudiesSemantic proximity
Metformin and Severe Post-COVID-19 Outcomes Among Individuals with Diabetes MellitusSemantic proximity
Metformin at the time of Covid-19 infection and risk of Long Covid: A Target Trial Emulation StudySemantic proximity
Viral clearance as a surrogate of clinical efficacy for COVID-19 therapies in outpatients: A systematic review and meta-analysisSemantic proximity
How the clinical research community responded to the COVID-19 pandemic: An analysis of the COVID-19 clinical studies in ClinicalTrials.govSemantic proximity
GLP Medications and Severe Post-COVID-19 Outcomes Among Individuals with Type 2 Diabetes MellitusSemantic proximity
Comparative effectiveness of sotrovimab and molnupiravir for prevention of severe COVID-19 outcomes in non-hospitalised patients: an observational cohort study using the OpenSAFELY platformSemantic proximity
Inhaled Fluticasone for Outpatient Treatment of Covid-19: A Decentralized, Placebo-controlled, Randomized, Platform Clinical TrialSemantic proximity
A snapshot of the ongoing clinical research on COVID-19Semantic proximity
Assessment of Nirmatrelvir-Ritonavir Effects on Acute and Post-Acute COVID-19 Illness in US Adolescents: Target Trial EmulationSemantic proximity
Select a neighboring publication to make it the new centre.