Article

Deep metagenomics examines the oral microbiome during dental caries, revealing novel taxa and co-occurrences with host molecules

2019-10-15

Abstract excerpt

Dental caries is the most common chronic infectious disease globally. The microbial communities associated with caries have mainly been examined using relatively low-resolution 16S rRNA gene amplicon sequencing and/or using downstream analyses that are unsound for the compositional nature of the data provided by sequencing. Additionally, the relationship between caries, oral microbiome composition, and host immuno...

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Literature Corpus work: b755dd50-f584-553b-ad5a-9db5b6ced7b9
DOI: 10.1101/804443

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