Article

Molecular genetics of hemophilia A: Clinical perspectives

2010-11-01

Abstract excerpt

Since the publication of the sequence of the factor VIII (F8) gene in 1984, a large number of mutations that cause hemophilia A have been identified and a significant progress has been made in translating this knowledge for clinical diagnostic and therapeutic purposes. Molecular genetic testing is used to determine the carrier status, for prenatal diagnosis, for prediction of the likelihood of inhibitor developmen...

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Literature Corpus work: b744a3ae-c23e-5a4e-851f-91724233d9c4
DOI: 10.1016/j.ejmhg.2010.10.005

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