Article

Genome-Wide mRNA Profiling Identifies  the NRF2- Regulated Lymphocyte Oxidative Status in Patients with Silicosis

2021-03-06

Abstract excerpt

<h4>Background: </h4> The immunomodulatory abnormalities of silicosis are related to the lymphocyte oxidative state. The potential effect of antioxidant therapy on silicosis may depend on the variation in nuclear factor erythroid 2-related factor 2 (NRF2)-regulated antioxidant genes in peripheral blood mononuclear cells (PBMCs). As NRF2 is a redox-sensitive transcription factor, its possible roles and underlying m...

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Literature Corpus work: b65c1da8-4da2-5a92-9e49-a4b3949fe0ff
DOI: 10.21203/rs.3.rs-270262/v1

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