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High level of FANCI correlates with worse prognostic outcome and promotes tumor growth of lung adenocarcinoma partly by suppressing the activation of M1 macrophages

2022-08-17

Abstract excerpt

FANCI, as a member of the Fanconi anemia (FA) complementation group, normally associates with FANCD2 to play an important role in ribosome biogenesis and DNA repair. However, the correlation of FANCI to prognostic value and the molecular mechanism in lung adenocarcinoma (LUAD) patients remain unclear. In the present paper, bioinformatics analysis was performed on LUAD data from TCGA and GEO database, and further t...

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Literature Corpus work
b64a216e-4aa7-5e80-8126-458caed06a04
DOI
10.21203/rs.3.rs-1929672/v1
Open publication

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High level of FANCI correlates with worse prognostic outcome and promotes tumor growth of lung adenocarcinoma partly by suppressing the activation of M1 macrophagesDOI 10.21203/rs.3.rs-1929672/v1
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