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Whole-exome Sequencing Identify Rare Variants in Novel Candidate Genes with Non-syndromic Patent Ductus Arteriosus

2021-01-15

Abstract excerpt

<h4>Background: </h4> Patent Ductus Arteriosus (PDA) is one of the most common congenital heart defects that can cause pulmonary hypertension, heart failure, and even death. Prior studies have suggested a role for genetics in determining spontaneous ductal closure, however the clinical characteristics and genetic cause underlying PDA remain unclear. <h4>Results: </h4> Therefore, to further explore genetic etiology...

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Literature Corpus work: b51e5e3f-a215-5ee8-818f-0251425acc5f
DOI: 10.21203/rs.3.rs-142511/v1

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