Article

Gaussian graphical modeling of the serum exposome and metabolome reveals interactions between environmental chemicals and endogenous metabolites involved in critical metabolic processes

2020-09-18

Abstract excerpt

<h4>ABSTRACT</h4> Given the complex exposures from both exogenous and endogenous sources that an individual experiences during life, exposome-wide association studies that interrogate levels of small molecules in biospecimens have been proposed for discovering causes of chronic diseases. We conducted a study to explore associations between environmental chemicals and endogenous molecules using Gaussian graphical m...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b4f5956c-35d0-54fa-9974-14ac6e96e788
DOI: 10.1101/2020.09.15.20190413

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Gaussian graphical modeling of the serum exposome and metabolome reveals interactions between environmental chemicals and endogenous metabolites involved in critical metabolic processesDOI 10.1101/2020.09.15.20190413Read

Gaussian graphical modeling of the serum exposome and metabolome reveals interactions between environmental chemicals and endogenous metabolitesSemantic proximity Read

Blurred lines: Crossing the boundaries between the chemical exposome and the metabolomeSemantic proximity Read

Integrated exposomic analysis of lipid phenotypes: Leveraging GE.db in environment by environment interaction studies.Semantic proximity Read

ENVESOME: The Environmental Exposome and HealthSemantic proximity Read

Multiomics Data Analyses Identified CpG Sites and Genes That Mediate the Impact of Exposure to Environmental Chemicals on Cardiometabolic TraitsSemantic proximity Read

Advancing translational exposomics: bridging genome, exposome and personalized medicine.Semantic proximity Read

Redefining environmental exposure for disease etiologySemantic proximity Read

The Exposome: Molecules to PopulationsSemantic proximity Read

Measuring the exposome: A powerful basis for evaluating environmental exposures and cancer riskSemantic proximity Read

State-of-the-art methods for exposure-health studies: Results from the exposome data challenge eventSemantic proximity Read

Future of environmental research in the age of epigenomics and exposomicsSemantic proximity Read

Beyond genomics: understanding exposotypes through metabolomics.Semantic proximity Read