Article

Biological Age Acceleration and Inflammatory Burden Identify Older ICU Patients at Higher Risk of Delirium: A MIMIC-IV Study with eICU Validation

2026-06-16

Abstract excerpt

<title>Abstract</title> <p> <bold>Objective:</bold> Delirium risk in older ICU patients is influenced by chronological age, acute illness severity, inflammation, and underlying vulnerability. This study derived KDM-core biological age acceleration (BAAccel) and PCA-derived inflammatory burden from routine laboratory biomarkers, examined their combined phenotypes in relation to ICU delirium risk, and externally...

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Literature Corpus work: b4ef67c5-d4f1-505d-bb92-d3b3367da3bd
DOI: 10.21203/rs.3.rs-9871382/v1

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