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Enhanced Postoperative Analgesic Effect of Hydromorphone Hydrochloride and Decreased Incidence of Pruritus via Continuous Low-dose Pumping of Nalmefene: A Randomized Controlled Study

2022-11-08

Abstract excerpt

<h4>Background: </h4> Hydromorphone hydrochloride has a satisfactory effect on postoperative analgesia for patients with colorectal cancer, yet accompanied by a relatively incidence of adverse events. Low-dose naloxone combined with opioids for Patient Controlled Analgesia (PCA) can reduce the incidence of drug-related adverse events. Meanwhile, Nalmefene is a more selective opioid receptor antagonist than naloxon...

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Literature Corpus work
b4ad0c44-a36d-594b-8b5a-08ab617aadb6
DOI
10.21203/rs.3.rs-2161696/v1
Open publication

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Enhanced Postoperative Analgesic Effect of Hydromorphone Hydrochloride and Decreased Incidence of Pruritus via Continuous Low-dose Pumping of Nalmefene: A Randomized Controlled StudyDOI 10.21203/rs.3.rs-2161696/v1
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