Article

Engineered skin microbiome-assisted delivery to the pilosebaceous unit

2023-04-06

Abstract excerpt

<title>Abstract</title> <p>Microbes are fascinating molecular machines which can be equipped with synthetic genetic programs that allow them to produce therapeutic molecules targeted on demand upon disease sensing. <italic>Cutibacterium acnes</italic> engraftment capacity and living habitat close to important pharmacological targets makes it an attractive chassis to create skin living therapeutics. Here, we repor...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b43fbccc-1dab-536e-83ff-2f2ef90fe569
DOI: 10.21203/rs.3.rs-2660218/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Engineered skin microbiome-assisted delivery to the pilosebaceous unitDOI 10.21203/rs.3.rs-2660218/v1Read

<i>Cutibacterium acnes</i> antibiotic production shapes niche competition in the human skin microbiomeSemantic proximity Read

Recent advances in single-cell engineered live biotherapeutic products research for skin repair and disease treatmentSemantic proximity Read

New insights into the role of Cutibacterium acnes-derived extracellular vesicles in inflammatory skin disordersSemantic proximity Read

A Janus-Faced Bacterium: Host-Beneficial and -Detrimental Roles of Cutibacterium acnesSemantic proximity Read

From Dysbiosis to Healthy Skin: Major Contributions of Cutibacterium acnes to Skin HomeostasisSemantic proximity Read

SkinCom, a synthetic skin microbial community, enables reproducible investigations of the human skin microbiomeSemantic proximity Read

Controlling skin microbiome as a new bacteriotherapy for inflammatory skin diseasesSemantic proximity Read

Microbe Interactions within the Skin MicrobiomeSemantic proximity Read

Interference and co-existence of staphylococci and Cutibacterium acnes within the healthy human skin microbiomeSemantic proximity Read

Mechanisms for control of skin immune function by the microbiomeSemantic proximity Read

Gram‐negative anaerobes elicit a robust keratinocytes immune response with potential insights into <scp>HS</scp> pathogenesisSemantic proximity Read

Cutibacterium acnes and Staphylococcus epidermidis: the unmissable modulators of skin inflammatory responseSemantic proximity Read