Article

Gonadal Dysfunction in Wolfram Syndrome: A Prospective Study

2025-04-16

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> Wolfram syndrome (WFS), also known as DIDMOAD, is a rare monogenic neurodegenerative disorder characterized by 4 key components: non-autoimmune insulin-dependent diabetes mellitus (DM), optic atrophy, sensorineural hearing loss, and diabetes insipidus. Although it significantly affects quality of life, gonadal dysfunction, particularly hypogonadism, remains unde...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b3e71913-c654-5cfa-a39b-ad08ed1ad29d
DOI: 10.21203/rs.3.rs-6403130/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Gonadal Dysfunction in Wolfram Syndrome: A Prospective StudyDOI 10.21203/rs.3.rs-6403130/v1Read

Wolfram Syndrome 1: A Pediatrician's and Pediatric Endocrinologist's Perspective.Semantic proximity Read

A rare cause of hypergonadotropism reported for the first time; ‘DiGeorge Syndrome’Semantic proximity Read

Current developments in Wolfram syndrome.Semantic proximity Read

State of the art review in gonadal dysgenesis: challenges in diagnosis and managementSemantic proximity Read

Wolfram Syndrome: A Case Report and Review of Clinical Manifestations, Genetics Pathophysiology, and Potential TherapiesSemantic proximity Read

Wolfram syndrome.Semantic proximity Read

Nonobstructive azoospermia: an etiologic reviewSemantic proximity Read

Wolfram Syndrome 1: A Neuropsychiatric Perspective on a Rare DiseaseSemantic proximity Read

Savelyeva LV. Isolated hypogonadotropic hypogonadism caused by a mutation in the WDR11 gene: a clinical case reportSemantic proximity Read

The Retrospective Evaluation Of Endocrine Manifestations In Chinese Patients With Wilson’s DiseaseSemantic proximity Read

The evaluation of ovarian function in normosmic idiopathic hypogonadotropic hypogonadism with a fibroblast growth factor receptor 1 mutation: a case report.Semantic proximity Read

Wolfram Syndrome 1: A Neuropsychiatric Perspective on a Rare Disease.Semantic proximity Read