Article

Presence of Lipid Vacuoles in Kupffer Cells as a Marker for Early Detection of Niemann-Pick Disease Type C in Neonatal Cholestasis

2021-09-15

Abstract excerpt

<title>Abstract</title> <p>Background Early diagnosis of Niemann<bold>-</bold>Pick disease type C (NP-C) is the key for reduction of organ damage since a medical treatment is available now. However, early detection of patients with a high clinical suspicion of NP-C in neonatal cholestasis is still challenging. Plasma oxysterol studies demonstrate a relatively low specificity for NP-C in neonatal cholestatic pati...

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Literature Corpus work: b2c0b5ad-3117-5ab8-8313-d0e9546ba1f2
DOI: 10.21203/rs.3.rs-898453/v1

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