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Syndrome of Inappropriate Antidiuretic Hormone Secretion and Thrombotic Microangiopathy as Paraneoplastic Syndromes Complicating BRCA2-Mutated Metastatic Prostate Cancer

2025-10-20

Abstract excerpt

<h4>Background: </h4> Metastatic prostate cancer with BRCA2 mutation is associated with aggressive clinical behavior and poor outcomes with standard systemic therapy. While the BRCA2 mutation predicts response to PARP inhibitors and platinum agents, its association with paraneoplastic syndromes is not well described.Case Presentation: We report a 72-year-old male who presented with altered sensorium with severe hy...

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Literature Corpus work
b23d20ac-c38b-5327-9e56-208bb6f0df27
DOI
10.20944/preprints202510.1449.v1
Open publication

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