Article

SadB acts as a master regulator modulating <i>Pseudomonas aeruginosa</i> pathogenicity

2025-09-15

Abstract excerpt

<h4>ABSTRACT</h4> Pseudomonas aeruginosa sadB mutants exhibit a hyper-swarming, biofilm defective phenotype. To acquire insights into the in vivo contribution of sadB to virulence in a mouse soft tissue infection model, we employed bioluminescence imaging and histopathology. Compared with the parent PAO1 strain, the Δ sadB mutant was highly attenuated and rapidly cleared from the infection site whereas genetic...

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Literature Corpus work: b0fd1d66-2d7d-512d-9ba0-d7ed9e01b0ee
DOI: 10.1101/2025.09.11.675511

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