Article

Insufficiency of PCR diagnostics for Detection of Diarrhoeagenic<i>Escherichia coli</i>in Ibadan, Nigeria

2023-01-09

Abstract excerpt

Understanding the contribution of different diarrhoeagenic Escherichia coli pathotypes to disease burden is critical to mapping risk and informing vaccine development. Targeting select virulence genes by PCR is the diagnostic approach of choice in high-burden, least-resourced African settings. We compared the performance of a commonly-used multiplex protocol to whole genome sequencing (WGS). PCR was applied to 3,8...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b0959c3e-b1dd-515c-a534-106e09c125b4
DOI: 10.1101/2023.01.06.23284276

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Insufficiency of PCR diagnostics for Detection of Diarrhoeagenic<i>Escherichia coli</i>in Ibadan, NigeriaDOI 10.1101/2023.01.06.23284276Read

PCR diagnostics are insufficient for the detection of Diarrhoeagenic Escherichia coli in Ibadan, NigeriaSemantic proximity Read

Molecular Epidemiology of Diarrhoeagenic<i>Escherichia coli</i>in Africa: A Systematic Review and Meta-AnalysisSemantic proximity Read

Enteroaggregative <i>Escherichia</i> clade I from NigeriaSemantic proximity Read

Epidemiology and risk factors for diarrhoeagenic <i>Escherichia coli</i> carriage among children in northern Ibadan, NigeriaSemantic proximity Read

Genomic epidemiology of enteropathogenic <i>Escherichia coli</i> (EPEC) in southwestern NigeriaSemantic proximity Read

Molecular approaches in the diagnosis of diarrhoeal disease in children from rural GambiaSemantic proximity Read

Whole genome characterisation of Enterotoxigenic<i>Escherichia coli</i>circulating in ZambiaSemantic proximity Read

Whole Genome Sequencing Reveals <i>Enterobacter hormaechei</i> as a Key Bloodstream Pathogen in Six Tertiary Care Hospitals in Southwestern NigeriaSemantic proximity Read

Genetic basis for antimicrobial resistance in <i>Escherichia coli</i> isolated from household water in municipal Ibadan, NigeriaSemantic proximity Read

An ST131 clade and a Phylogroup A clade bearing a novel <i>Escherichia coli</i> O-antigen cluster predominate among bloodstream <i>E. coli</i> isolates from southwest Nigeria hospitalsSemantic proximity Read

Phenotypic markers misclassify isolates of<i>Salmonella typhimurium</i>as<i>S. typhi</i>, but were correctly identified by whole genome sequencing during a septicemia study in western KenyaSemantic proximity Read

Genomic diversity of pathogenic multidrug-resistant <i>Escherichia coli</i> across asymptomatic children and livestock in Nairobi, KenyaSemantic proximity Read