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GWAS of Retinal Vessel Tortuosity Identifies 173 Novel Loci Revealing Genes and Pathways Associated with Vascular Pathomechanics and Cardiometabolic Diseases

2020-06-26

Abstract excerpt

<h4>Background</h4> Fundus images allow for non-invasive assessment of the retinal vasculature whose features provide important information on health. Blood vessel tortuosity is a morphological feature associated with many diseases including hypertension. <h4>Methods</h4> We analyzed 116 639 fundus images of suitable quality from 63 662 participants from three cohorts, namely the UK Biobank (n = 62 751), SKIPOGH (...

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Literature Corpus work
b02b56a0-93cf-5f68-81f9-e7660527ed7a
DOI
10.1101/2020.06.25.20139725
Open publication

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