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Single-cell Resolution Spatial Transcriptomics Delineates the Inflammatory Landscape of Human Dental Pulp: Regional Crosstalk and Therapeutic Implications

2025-07-29

Abstract excerpt

<title>Abstract</title> <p>This study utilized single-cell resolution spatial transcriptomics (Visium HD) to investigate the spatial cellular architecture and molecular interactions in healthy and inflamed dental pulp, aiming to explore the pathological mechanisms of pulpitis and identify novel targets for vital pulp therapy. Spatial transcriptomic sequencing was performed on dental pulp tissues from two healthy...

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Literature Corpus work
afc51fda-3fb9-5fc1-a2a8-71e0ae58e3cb
DOI
10.21203/rs.3.rs-7096435/v1
Open publication

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Single-cell Resolution Spatial Transcriptomics Delineates the Inflammatory Landscape of Human Dental Pulp: Regional Crosstalk and Therapeutic ImplicationsDOI 10.21203/rs.3.rs-7096435/v1
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