Article

Knowledge-Based Prioritization of Genomic Variations: A Quest for Detailed Understanding the Genetic Architecture of Diseases

2023-10-02

Abstract excerpt

Understanding the genetic architecture of a disease is crucial for development of valid diagnostic and therapeutic interventions. The analysis of genomic variations associated with pathological conditions is the starting point for uncovering disease-causing pathways (candidate processes). However, the complexity of intergenic and genetic-environmental interactions hinders the identification of pathogenic values of...

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Literature Corpus work: afbba893-7b71-59c2-8c3c-e3999d0ccb78
DOI: 10.20944/preprints202310.0038.v1

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