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Pharmacological Dose of Vitamin C Promotes Apoptosis by Induces Caspases -3 to -9, Inhibits Matrix Metalloproteinases, Reduces Cell Cycle Proteins, and Enhances Tumor Suppressor Genes Expression in Triple-Negative Breast Cancer Cells

2024-10-15

Abstract excerpt

Breast cancer is currently the second leading cause of death worldwide, accounting for 15% of all deaths (8.2 million deaths). Approximately 20% of breast cancer diagnoses are triple-negative breast cancer (TNBC), a type of cancer that lacks receptors for estrogen (ER negative), progesterone (PR negative), and human epidermal growth factor receptor 2 (HER2/neu negative). Consequently, TNBC doesn’t respond to...

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Literature Corpus work: af48c8e5-6bce-5ab7-8546-d59a4bfa645a
DOI: 10.20944/preprints202410.1201.v1

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Pharmacological Dose of Vitamin C Promotes Apoptosis by Induces Caspases -3 to -9, Inhibits Matrix Metalloproteinases, Reduces Cell Cycle Proteins, and Enhances Tumor Suppressor Genes Expression in Triple-Negative Breast Cancer CellsDOI 10.20944/preprints202410.1201.v1Read

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