Article
Phylogenetically based establishment of a dengue virus panel, representing all available genotypes, as a tool in dengue drug discovery
2018-10-11
Abstract excerpt
Dengue fever is the most widespread of the human arbovirus diseases, with approximately one third of the world’s population at risk of infection. Dengue viruses are members of the genus Flavivirus (family Flaviviridae ) and, antigenically, they separate as four closely related serotypes (1-4) that share 60 to 75 % amino acid homology. This genetic diversity complicates the process of antiviral drug discovery. Th...
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Identifiers and source
- Literature Corpus work
- aefa77c0-485a-5ab1-9438-b5e55ca5806d
- DOI
- 10.1101/439695