Article

High-quality human preimplantation embryos stimulate endometrial stromal cell migration via secretion of microRNA hsa-miR-320a

2020-01-24

Abstract excerpt

Implantation failure is one of the major success limiting factors in human reproduction. Despite, the mechanisms that determine successful human embryo implantation remain largely unknown. We here show that high-quality human preimplantation embryos secrete soluble signaling factors, including micro RNA (miRNA) hsa-miR-320a, that promote migration of human endometrial stromal cells (hESCs). By using miRNA mimics a...

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Literature Corpus work: aef69585-5160-5057-86ef-8bd093fc1758
DOI: 10.1101/2020.01.21.913632

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