Article

Domain-Specific Effects of GABA-Modulating Pharmacotherapies in Autism Spectrum Disorder: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

2026-08-23

Abstract excerpt

<h4>Background: </h4> Altered gamma-aminobutyric acid (GABA) neurotransmission is a proposed mechanism underlying autism spectrum disorder (ASD), prompting evaluation of several GABA-modulating pharmacotherapies. However, it remains unclear whether these interventions improve ASD broadly or preferentially affect specific symptom domains. <h4>Methods:</h4> We conducted a systematic review and random-effects meta-an...

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Literature Corpus work: aec1713d-4058-5cb5-bf7b-9a3865ac1484
DOI: 10.64898/2026.08.23.26361086

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