Article

SLC38A1 as a novel therapeutic target in upper tract urothelial carcinoma via regulating cell proliferation and migration through suppressing Akt/mTOR signaling

2024-12-18

Abstract excerpt

<title>Abstract</title> <p>Upper tract urothelial carcinoma (UTUC) has specific high prevalence in Asian population and, compared to bladder cancer, there are unique etiologic and genomic factors contributing to its tumorigenesis. Although up-regulation of sodium-coupled neutral amino acid transporter 1 (SLC38A1) gene has been previously implicated as a promising therapeutic target for many tumors, the role of SL...

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Literature Corpus work: aeaee7a8-4f85-574f-a4d6-b4db64cbc3d5
DOI: 10.21203/rs.3.rs-5635396/v1

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