Multimodal AI-driven Biomarker for Early Detection of Cancer Cachexia

Abstract excerpt

Cancer cachexia, a multifactorial metabolic syndrome characterized by severe muscle wasting and weight loss, contributes to poor outcomes across various cancer types but lacks a standardized, generalizable biomarker for early detection. We present a multimodal AI-based biomarker trained on real-world clinical, radiologic, laboratory, and unstructured clinical note data, leveraging foundation models and large langu...

Topics

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• Algorithms
• Cachexia
• Machine Learning
• Neoplasms
• Phenotype

Identifiers and source

Literature Corpus work

ade521e8-6ce4-54fa-9b0f-4d421e754877

DOI

10.1101/2025.09.17.25336028