Individualized Lipid Metabolism-Associated Six-Gene Signature for Prediction of Overall Survival, Immune Infiltration, Immunotherapy Response, and Potential Candidate Drugs in Lung Squamous Cell Carcinoma Patients: Development and Validation

Abstract excerpt

<h4>Background: </h4> Disordered lipid metabolism is a novel hallmark of cancer initiation. However, the role of lipid metabolism-associated genes (LAGs) in the immune microenvironment, the prognosis, and the overall survival of lung squamous cell carcinoma (LUSC) remain unclear. <h4>Methods: </h4> This study examined 1064 LAGs in 502 LUSC tumors and 49 normal lung tissues from the Cancer Genome Atlas lung squamou...

Topics

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• Biomarkers, Tumor
• Carcinoma, Non-Small-Cell Lung
• Carcinoma, Squamous Cell
• Cytochrome P-450 Enzyme System
• Gene Expression Regulation, Neoplastic
• Lipid Metabolism
• Lung
• Phospholipases A

Identifiers and source

Literature Corpus work

ad59bd1d-8b3c-58fd-b90c-61c82d087b47

DOI

10.21203/rs.3.rs-2713469/v1