Is a Synaptic Dysfunction the Origin of Autism?

Abstract excerpt

Autism in childhood is a heterogeneous disease with around 110 phenotypes. Around 800 genes are affiliated with autism including members of neuro-ligand, neurexin, cadherin, GABA receptors, SHANK gene families, mutated UBE3 A on chromosome 15 and SNORD 116 precursor interaction. A predominant 4:1 male to female ratio is found in autistic spectrum disorder. 50 per cent of all autistic children show chromosome delet...

Topics

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• Autistic Disorder
• Central Nervous System
• Chromosomes, Human, Pair 15
• Chromosomes, Human, Pair 16
• Chromosomes, Human, Pair 2
• Chromosomes, Human, Pair 7
• Fragile X Syndrome
• Tuberous Sclerosis

Identifiers and source

Literature Corpus work

ad2bf722-bb13-5939-bad7-359e44fc0859

DOI

10.20944/preprints202410.2314.v1