Article

Ferroptosis Transcriptional Regulation and Prognostic Impact in Medulloblastoma Subtypes Revealed by scRNA-seq

2024-12-11

Abstract excerpt

Medulloblastoma (MB) is the most common malignant brain tumor in children, typically arising during infancy and childhood. Despite multimodal therapies achieving a response rate of 70% in children older than 3 years, treatment remains challenging. Ferroptosis, a form of regulated cell death, can be induced in medulloblastoma cells in vitro using erastin or RSL3. Using two independent medulloblastoma RNA-sequencing...

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Literature Corpus work: ad09cdf2-72ae-5521-9365-97c8e20c7178
DOI: 10.20944/preprints202412.0982.v1

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