Article

Dengue Protease-Mediated Activation and Polarization of Macrophages

2024-11-24

Abstract excerpt

Controlled activation of macrophages to achieve desired phenotypes in vivo and in vitro could lead to possible treatments for several inflammatory and proliferative diseases. This investigation uniquely established that dengue protease enhances the polarization and activation of human and murine macrophages following extracellular exposure. It was observed that macrophages have a robust response to extracellularly...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: acf4f308-f554-5391-a6e3-3d1a3809a3e3
DOI: 10.1101/2024.11.23.624958

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Dengue Protease-Mediated Activation and Polarization of MacrophagesDOI 10.1101/2024.11.23.624958Read

Distinct regulation of dengue virus-induced inflammasome activation in humanmacrophage subsetsSemantic proximity Read

M2 macrophage subset decrement is an indicator of bleeding tendency in pediatric dengue disease.Semantic proximity Read

Peritoneal M2 macrophage-derived extracellular vesicles as natural multi-target nanotherapeutics to attenuate cytokine storm after severe infectionsSemantic proximity Read

Dengue infection of monocytic cells activates ER stress pathways, but apoptosis is induced through both extrinsic and intrinsic pathwaysSemantic proximity Read

Replication of Dengue Virus in K562-Megakaryocytes Induces Suppression in the Accumulation of Reactive Oxygen SpeciesSemantic proximity Read

Macrophages and cytokines in the early defence against herpes simplex virusSemantic proximity Read

Dengue NS1 interaction with lipids alters its pathogenic effects on monocyte derived macrophagesSemantic proximity Read

Role of intracellular events in the pathogenesis of dengue; An overviewSemantic proximity Read

<i>Kabasura Kudineer Choornam</i> , a medicinal polyherbal formulation, modulates human macrophage polarization and phagocytic functionSemantic proximity Read

Immune-mediated cytokine storm and its role in severe dengue.Semantic proximity Read

Proinflammatory responses in SARS-CoV-2 infected and soluble spike glycoprotein S1 subunit activated human macrophagesSemantic proximity Read

Essential role of RIG-I in the activation of endothelial cells by dengue virusSemantic proximity Read