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The Importance of Early Intervention in Ruptured Cerebral Aneurysm: Biochemical and Pathophysiological Foundations Within the First 24 Hours

2026-03-24

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<title>Abstract</title> <p> <bold>Background:</bold> Severe vasospasm in cases of subarachnoid hemorrhage (SAH) due to ruptured cerebral aneurysms accounts for a high mortality rate ranging from 36% to 67%, as well as permanent neurological deficits. Biochemical changes involving neuropeptides such as Neuropeptide Y (NPY) and Calcitonin Gene-Related Peptide (CGRP) have been studied as regulators of vascular ton...

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Literature Corpus work: ab0a1a61-0da5-586c-9550-32e745c46b41
DOI: 10.21203/rs.3.rs-9034232/v1

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